Elon Musk @elonmusk
Replying to @michaelmina_lab
In your opinion, at what Ct number for the cov2 N1 gene should a PCR test probably be regarded as positive? If I’m asking the wrong question, what is a better question?
Michael Mina @michaelmina_lab
·
6h
Replying to @elonmusk
Great question! It’s more complex question and depends on why the test is being used - ie: do you want to know if you are currently contagious/risky to others or if you have any remnants of RNA? The difference may sound trivial but it is massive
If the question is "Am I currently infectious right now when the swab is collected" then on *most* instruments/labs, data suggests a Ct value somewhere around 30 or below is needed. (Different instruments/labs are different - but that's a decent generalization)...
If the question is "Am I becoming infectious" then even if you have a high Ct value... say 38... then it's important to test again the next day. If you go to 28, then you better stay put, you're likely infectious for the next 5-8 days or so...
If you stay at ~38 or you went from 32 to 35 or something over a 24 hour period - then most likely you are recovering from infection and no longer infectious. Some people stay positive after infection with Cts in mid-upper 30's for weeks/months.
If want to know if one is a danger to others RIGHT NOW... a rapid antigen test can be your best friend. If positive, immediately confirm with a second *different* rapid test (antigen / lamp / isothermal) or get a PCR - but it has a long turnaround time so not as useful.
If you just want to know the question that doctors often ask: "Do I have evidence of a SARS-CoV-2 infection" then look for the RNA with a PCR test or PCR-like test. In this case, a Ct value <40 is usually considered reliable on most tests for "Do I have any virus RNA in me"..
If you actually get a result with a Ct value of 40 though... that's really REALLY low... and can be a false positive. Many labs/tests have decided to use a cutoff an order of magnitude higher.... choosing a Ct value of 37 or lower to be positive.
Again though - PCR is tough to interpret. It does NOT = infectious. If <30... generally = contagious-ish. <20 DEFINITELY high virus
More time is in post-infectious PCR+ stage than infectious PCR+... this is where antigen test shines. If +ve and confirmed... means contagious
15 Nov 2020, 10:01:54 @DeeCee rakstīja:
Te interesants thread, cik reizes atkārto un kāpēc
te ir ļoti labs jautājums viņam:
@elonmusk @michaelmina_lab The approved tests are almost all set at 40. But I do agree with others that are asking … what is your end game here? To use influence to create a greater resistance to stopping the pandemic? What benefit is this to you? Regular people likely don’t even get what you’re saying.
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
kur tu visu šito sūdu atrodi? Speciāli meklē?
gūgles plašumu fenomens- ko gribi, to atrodi. Ja preizi uzjautāsi, tad atradīsi stāstu, kā trīs teroristi nomira ar koronu (viens inficēja divus citus, jo bija diy veikalā pēc skrūvēm, kur saķēra to draņķi no vienas mājsaimnieces, kura savukārt blablabla). Šie bija paņēmuši ķīlniekus, kuru priekšā paši vēlāk klepojot atdeva galus un ķīlnieki vienkārši aizgāja mājās Happy end!
pietiks Tev smieties! labāk pastāsti man šo - ja man ir Kolēģi - A, B, C, D un E! ar katru no viņiem es dienā sēžu pie viena datora kādu brīdi, viņi savā starpā satiekas un mums ir kopīgās sapulces katru nedēļu, viss cool! Kādēļ es ar kolēģi A un B nedrīkstu vakarā paskatīties kopā futbola spēli?
es zinu - tādi ir MK noteikumi šobrīd, bet pēc būtības? Tu te nospridžīji, ka visi lohi, kuri to nesaprot
Tāpēc, ka lielākā daļa , kas ies skatīties spēli nebūs kolēģi un tikai dēļ Tevis un Taviem kolēģiem nekāda spēles skatīšanās nenotiks izsekot, vai tiešām esiet kolēģi utt, arī jebatorijs
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
kur tu visu šito sūdu atrodi? Speciāli meklē?
twitterī nesen bija izlecis, iemetu saistībā ar tītara bērēm, jo aprakstīts kā no 1 slimnieka var samērā daudz slimo sanākt, tā pat kā tajā LV gadījumā
twitterī nesen bija izlecis, iemetu saistībā ar tītara bērēm, jo aprakstīts kā no 1 slimnieka var samērā daudz slimo sanākt, tā pat kā tajā LV gadījumā
man šķiet nav jābūt ģēnijam un nav jālasa speciāli raksti, lai saprastu, ka no viena slmnieka var sanākt daudz slimo
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
kur tu visu šito sūdu atrodi? Speciāli meklē?
twitterī nesen bija izlecis, iemetu saistībā ar tītara bērēm, jo aprakstīts kā no 1 slimnieka var samērā daudz slimo sanākt, tā pat kā tajā LV gadījumā
Nu zin kaa, buusim korekti. Tu pljuutii kaa delfi utt. Slimie. Cik no inficeetajiem (tas buutu pareizs apziimeejums) reaali saslimst? Cim saslimst nopietni? Tev tak taa patiik stat. cipari. Pastaasti.
pietiks Tev smieties! labāk pastāsti man šo - ja man ir Kolēģi - A, B, C, D un E! ar katru no viņiem es dienā sēžu pie viena datora kādu brīdi, viņi savā starpā satiekas un mums ir kopīgās sapulces katru nedēļu, viss cool! Kādēļ es ar kolēģi A un B nedrīkstu vakarā paskatīties kopā futbola spēli?
es zinu - tādi ir MK noteikumi šobrīd, bet pēc būtības? Tu te nospridžīji, ka visi lohi, kuri to nesaprot
nu lūdzu esi precīzāks, tā es neteicu. es teicu, ka tu esi lohs, ja tu nesaproti kāpēc tu vari ar astoņiem kolēģiem sēdēt pie viena konferenču galda, bet nevari iet vakarā ar visiem kost.
Only 55 people attended the Aug. 7 reception at the Big Moose Inn in Millinocket. But one of those guests arrived with a coronavirus infection. Over the next 38 days, the virus spread to 176 other people. Seven of them died.
None of the victims who lost their lives had attended the party.
kur tu visu šito sūdu atrodi? Speciāli meklē?
twitterī nesen bija izlecis, iemetu saistībā ar tītara bērēm, jo aprakstīts kā no 1 slimnieka var samērā daudz slimo sanākt, tā pat kā tajā LV gadījumā
Nu zin kaa, buusim korekti. Tu pljuutii kaa delfi utt. Slimie. Cik no inficeetajiem (tas buutu pareizs apziimeejums) reaali saslimst? Cim saslimst nopietni? Tev tak taa patiik stat. cipari. Pastaasti.
šķiet šeit kkur arī bija šis
protams, atkarībā no populācijas veselības stāvokļa un vecuma cipari var mainīties
Offline
Happy end!
